Research Article
A Genetic Variant in miRNA-219-1 Is Associated with Risk of Esophageal Squamous Cell Carcinoma in Chinese Kazakhs
Figure 2
miR-219-1-5p expression level in ESCC tissues. (a) miR-219-1-5p levels were determined in normal tissue and tumor tissue samples from ESCC patients () by qRT-PCR. All values were normalized to U6 RNA levels. Mean expression levels were 3.732 × 10−3 in normal tissue sample and 7.840 × 10−3 in tumor tissue sample (). (b) miR-219-1-5p levels were determined for different genotype in normal tissue and tumor tissue samples from ESCC patients (). All values were normalized to U6 RNA levels. Mean expression levels for rs107822 genotypes are 9.4 × 10−3 (GG, normal), 4.0 × 10−4 (GA, normal), and 5.0 × 10−4 (AA, normal) and 2.1 × 10−2 (GG, tumor), 3.0 × 10−4 (GA, tumor), and 4.0 × 10−4 (AA, tumor). , ; , .
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