A Genetic Variant in miRNA-219-1 Is Associated with Risk of Esophageal Squamous Cell Carcinoma in Chinese Kazakhs

Table 1

Characteristics of ESCC cases and controls.

Variables	Cases [ (%)]	Controls [ (%)]	value
	n = 248	n = 300
Age (years), mean ± SD	56.23 (±9.02)	55.16 (±10.62)	0.212
Age (years)			0.334
<57	122 (49.2)	160 (53.3)
≥57	126 (50.8)	140 (46.7)
Sex			0.212
Male	143 (57.7)	157 (52.3)
Female	105 (42.3)	143 (47.7)
Differentiation status
Well-differentiated	47 (19.0)
Moderately differentiated	152 (61.2)
Poorly differentiated	49 (19.8)
Tumor location
Upper	14 (5.6)
Middle + lower	234 (94.4)
Depth of invasion
T1/T2	98 (42.2)
T3/T4	134 (57.8)
Lymph node metastasis
No	132 (53.2)
Yes	116 (46.8)
Tumor node metastasis stage
I-II	154 (64.7)
III-IV	84 (35.3)

Two-sided   test.
Student’s -test.