Research Article
A Genetic Variant in miRNA-219-1 Is Associated with Risk of Esophageal Squamous Cell Carcinoma in Chinese Kazakhs
Table 1
Characteristics of ESCC cases and controls.
| Variables | Cases [ (%)] | Controls [ (%)] | value | n = 248 | n = 300 |
| Age (years), mean ± SD | 56.23 (±9.02) | 55.16 (±10.62) | 0.212 | Age (years) | | | 0.334 | <57 | 122 (49.2) | 160 (53.3) | | ≥57 | 126 (50.8) | 140 (46.7) | | Sex | | | 0.212 | Male | 143 (57.7) | 157 (52.3) | | Female | 105 (42.3) | 143 (47.7) | | Differentiation status | | | | Well-differentiated | 47 (19.0) | | | Moderately differentiated | 152 (61.2) | | | Poorly differentiated | 49 (19.8) | | | Tumor location | | | | Upper | 14 (5.6) | | | Middle + lower | 234 (94.4) | | | Depth of invasion | | | | T1/T2 | 98 (42.2) | | | T3/T4 | 134 (57.8) | | | Lymph node metastasis | | | | No | 132 (53.2) | | | Yes | 116 (46.8) | | | Tumor node metastasis stage | | | | I-II | 154 (64.7) | | | III-IV | 84 (35.3) | | |
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Two-sided test. Student’s -test.
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