Research Article
Serum Enzyme Profiles Differentiate Five Types of Muscular Dystrophy
Table 1
The demography and frequency of patients with MD presented with normal or abnormal serum enzymes levels.
| | Category | Age (y) | Gender (%) | ALTn (%) | ASTn (%) | ALPn (%) | LDHn (%) | CKn (%) | | Mean ± SD (range) | Male | Female | Normal | Abnormal | Normal | Abnormal | Normal | Abnormal | Normal | Abnormal | Normal | Abnormal |
| | DMD | 6.7 ± 3.4 (7 m–24) | 120 (100) | 0 (0) | 3 (2.5) | 119 (97.5) | 3 (2.5) | 119 (97.5) | 39 (32) | 83 (68) | 3 (2.5) | 119 (97.5) | 0 (0) | 122 (100) | | BMD | 13.0 ± 8.5 (2–37) | 36 (100) | 0 (0) | 0 (0) | 37 (100) | 0 (0) | 37 (100) | 16 (43.2) | 21 (56.8) | 0 (0) | 37 (100) | 0 (0) | 37 (100) | | FSHD | 25.8 ± 9.3 (13–50) | 13 (68) | 6 (32) | 5 (26.3) | 14 (73.7) | 12 (63.2) | 7 (36.8) | 10 (52.6) | 9 (47.4) | 11 (57.9) | 8 (42.1) | 1 (5.3) | 18 (94.7) | | LGMD | 22.6 ± 11.4 (3–54) | 23 (56) | 18 (44) | 11 (26.8) | 30 (73.2) | 9 (22.0) | 32 (78.0) | 24 (58.5) | 17 (41.5) | 10 (24.4) | 31 (75.6) | 1 (2.4) | 40 (97.6) | | EDMD | 15.4 ± 9.9 (6–42) | 6 (55) | 5 (45) | 8 (72.7) | 3 (27.3) | 7 (63.6) | 4 (36.4) | 4 (36.4) | 7 (63.6) | 6 (54.5) | 5 (45.5) | 3 (27.3) | 8 (72.7) |
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MD, muscular dystrophy; DMD, Duchenne muscular dystrophy; BMD, Becker’s muscular dystrophy; FSHD, facioscapulohumeral dystrophy; LGMD, limb girdle muscular dystrophy; EDMD, Emery-Dreifuss muscular dystrophy; ALT, alanine aminotransferase; AST, aspartate aminotransferase; ALP, alkaline phosphatase; LDH, lactic dehydrogenase; CK, creatine kinase; m, month.
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