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Disease Markers
Volume 2015, Article ID 546891, 10 pages
http://dx.doi.org/10.1155/2015/546891
Review Article

Ventilatory Efficiency in Children and Adolescents: A Systematic Review

1Department of Pediatrics, Faculty of Medical Sciences, State University of Campinas, Tessália Vieira de Camargo, 126 Cidade Universitária “Zeferino Vaz”, 13083-887 Campinas, SP, Brazil
2Department of Medical Genetics, Faculty of Medical Sciences, State University of Campinas, Tessália Vieira de Camargo, 126 Cidade Universitária “Zeferino Vaz”, 13083-887 Campinas, SP, Brazil
3State University of Santa Catarina, Center of Physical Education and Sports, Coqueiros, 88080-350 Florianópolis, SC, Brazil
4Department of Clinical Medics, Faculty of Medical Sciences, State University of Campinas, Tessália Vieira de Camargo, 126 Cidade Universitária “Zeferino Vaz”, 13083-887 Campinas, SP, Brazil

Received 5 March 2015; Revised 27 March 2015; Accepted 20 April 2015

Academic Editor: Robert Pichler

Copyright © 2015 Paloma Lopes Francisco Parazzi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Introduction. The index of ventilatory efficiency (VE/VCO2) obtained by the progressive exercise test has been considered the gold standard in the prognosis of adults with heart failure, but few studies have evaluated this approach in children. Objective. To verify the scientific evidence about the VE/VCO2 in pediatric and adolescents patients. Methods. A systematic literature review was carried out using the key words VE/VCO2, children, and adolescents using the PEDro and PubMed/MedLine databases. Clinical trials published from 1987 to 2014, including children, adolescents, and young adults up to 25 years, addressing the VE/VCO2 index as a method of evaluation, monitoring, and prognosis were considered. Results. Initially, 95 articles were found; 12 were excluded as the title/abstract did not contain the VE/VCO2 index or because they included patients greater than 25 years of age. From the remaining 83, 58 were repeated between the databases. The final sample consisted of 32 studies including healthy children and children with respiratory and other diseases. Conclusion. There are few studies involving cardiorespiratory assessment by ventilatory efficiency. The studies highlight the fact that high VE/VCO2 values are associated with a worse prognosis of patients due to the relationship with the decrease in pulmonary perfusion and cardiac output.