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Disease Markers
Volume 2015, Article ID 548951, 6 pages
Research Article

Evaluation of High Sensitive Troponin in Erectile Dysfunction

1Laboratorio di Analisi, Ospedale San Paolo, Dipartimento di Scienze della Salute, Università degli Studi di Milano, 20142 Milano, Italy
2Dipartimento di Malattie dell’Apparato Digerente e Medicina Interna, Ospedale Sant’Orsola-Malpighi, Alma Mater Studiorum, Università degli Studi di Bologna, 40138 Bologna, Italy
3Dipartimento di Scienze Biomediche per la Salute, Università degli Studi di Milano, 20133 Milano, Italy
4Dipartimento di Scienze Biomediche, Chirurgiche e Odontoiatriche, Università di Milano, 20133 Milano, Italy
5Istituto per la Sterilità e la Sessualità (ISES), 20123 Milano, Italy
6Unità Operativa Medicina di Laboratorio-1 Patologia Clinica, IRCCS Policlinico San Donato, San Donato Milanese, 20097 Milano, Italy

Received 21 May 2014; Revised 15 July 2014; Accepted 8 September 2014

Academic Editor: Johannes Mair

Copyright © 2015 Alessandra Barassi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Background. Evidence is accumulating in favour of a link between erectile dysfunction (ED) and coronary artery diseases. We investigated the presence of cardiac injury in patients who have had arteriogenic and nonarteriogenic ED using the hs-Tn levels. Methods. The diagnosis of ED was based on the International Index of Erectile Function 5-questionnaire (IIF-5) and patients were classified as arteriogenic (A-ED, ), nonarteriogenic (NA-ED, ), and borderline (BL-ED, ) patients in relation to the results of echo-color-Doppler examination of cavernous arteries. The level of hs-TnT and hs-TnI was measured in 120 men with a history of ED of less than one year with no clinical evidence of cardiac ischemic disease. Results. The levels of both hs-TnT and hs-TnI were within the reference range and there was no significant () difference between patients of the three groups. The hs-CRP values were higher in A-ED men compared with NA-ED () but not compared with BL-ED () and negatively correlated with IIF-5 (; ). Conclusions. In ED patients of the three groups the measurement of hs-Tn allows us to exclude the presence of cardiac involvement at least when the history of ED is less than one year and the men are without atherosclerotic risk factors.