Disease Markers / 2015 / Article / Tab 3

Research Article

Prognostic Value of High CXCR4 Expression in Renal Cell Carcinoma: A System Review and Meta-Analysis

Table 3

Subgroup analysis based on characteristics of various studies.

VariablesT/POverall survival
HR (95% CI)-squared (%)Model-He value value

Overall5/6052.77 (1.80, 4.27)51.7Random effect0.0664.61<0.001
Ethnicity
 Asian3/4393.78 (2.47, 5.78)0.0Fixed effect0.606.13<0.001
 Non-Asian2/1661.68 (1.14, 2.48)0.0Fixed effect0.352.630.009
Fuhrman grades III-IV (%)
 >701/621.48 (0.93, 2.37)NANANA1.640.102
 ≤704/5433.26 (2.27, 4.67)0.0Fixed effect0.4716.41<0.001
Median follow-up (months)
 >602/3292.70 (1.73, 4.21)0.0Fixed effect0.7274.39<0.001
 ≤603/2763.10 (1.24, 7.80)78.6Random effect0.0092.410.016

T/P: number of trials/number of patients, -He: value of heterogeneity.

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