Research Article

Urine Cell-Free DNA Integrity Analysis for Early Detection of Prostate Cancer Patients

Table 2

Sensitivity and specificity of different UCF-DNA integrity cut-off values in the overall case series.

Cut-off (ng/µL)SensitivitySpecificity

0.03
34/55 22/55
 Rate (95% CI)0.62 (0.48–0.75)0.40 (0.27–0.54)
0.04
32/55 24/55
 Rate (95% CI)0.58 (0.46–0.73)0.44 (0.30–0.58)
0.05
31/55 26/55
 Rate (95% CI)0.56 (0.42–0.70)0.47 (0.34–0.61)
0.06
28/55 27/55
 Rate (95% CI)0.51 (0.37–0.65)0.49 (0.35–0.63)

UCF: urine cell-free.