Urine Cell-Free DNA Integrity Analysis for Early Detection of Prostate Cancer Patients

Table 3

Sensitivity and specificity of UCF-DNA integrity and PSA.

	Sensitivity	Specificity
		Overall case series	Benign prostatic disease	Benign kidney and bladder disease	Others
PSA
	52/55	38/55	9/23	19/21	10/11
Rate	(0.95)	(0.69)	(0.39)	(0.91)	(0.91)
UCF-DNA integrity
	32/55	24/55	10/23	9/21	7/11
Rate	(0.58)	(0.44)	(0.43)	(0.43)	(0.64)

PSA cut-off value: 4 ng/mL.
UCF-DNA integrity cut-off value: 0.04 ng/µL.