Serum MicroRNA Profiles Serve as Novel Biomarkers for the Diagnosis of Alzheimer’s Disease

Figure 2

The concentrations of 4 identified serum miRNAs in Alzheimer’s disease (AD) cases and nondementia controls (NC) enrolled in the training and validation sets. The absolute concentrations of the 4 identified serum miRNAs in 48 AD and 48 NC of training set (a–d), as well as 79 AD and 75 NC of the validation set using a RT-qPCR assay (e–h). The absolute concentrations of the miRNAs were calculated based on the standard curves. Each point represents the mean of triplicate samples. Each value was derived from a nonparametric Mann-Whitney -test..

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