Research Article
Influence of GSTM1, GSTT1, and GSTP1 Polymorphisms on Type 2 Diabetes Mellitus and Diabetic Sensorimotor Peripheral Neuropathy Risk
Table 3
Genetic characteristics of studied patients with T2DM.
| | Variable |
DSPN No-42, No. (%) |
DSPN Yes-42, No. (%) | p value |
| | GSTM1 present/GSTT1 present | 16 (38.1) | 20 (47.1) | Reference | | GSTM1 null/GSTT1 null | 5 (11.9) | 6 (14.3) | 0.73, OR: 0.66
95% CI: (0.17–2.59) | | GSTM1 present/GSTT1 null | 2 (4.7) | 2 (4.7) | 0.95, OR: 0.80
95% CI: (0.10–6.32) | | GSTM1 null/GSTT1 present | 19 (45.2) | 14 (33.3) | 0.27, OR: 0.58
95% CI: (0.22–1.53) | | GSTP1/GSTT1/GSTM1 | | | | | Ile/Ile/ present/present | 13 (30.9) | 8 (19.1) | Reference | | Ile/Ile/ null/null | 4 (9.5) | 2 (4.7) | 0.98, OR: 0.81
95% CI: (0.12–5.5) | | Ile/Ile/ null/present | 2 (4.8) | 1 (2.4) | 0.98, OR: 0.81
95% CI: (0.06–10.48) | | Ile/Ile/ present/null | 7 (16.6) | 12 (28.5) | 0.11, OR: 2.78
95% CI: (0.77–10.1) | | Ile/Val/null/null | 0 (0.0) | 2 (4.8) | 0.17, OR: 7.9
95% CI: (0.33–186.4) | | Ile/Val/null/present | 0 (0.0) | 0 (0.0) | — | | Ile/Val/present/null | 5 (11.9) | 6 (14.3) | 0.46, OR: 1.95
95% CI: (0.44–8.55) | | Ile/Val/present/present | 6 (14.2) | 5 (11.9) | 0.72, OR: 1.35
95% CI: (0.30–5.94) | | Val/Val/null/null | 1 (2.4) | 1 (2.4) | — | | Val/Val/null/present | 0 (0.0) | 1 (2.4) | — | | Val/Val/present/null | 2 (4.8) | 2 (4.8) | 0.95, OR: 1.62
95% CI: (0.19–13.9) | | Val/Val/present/present | 0 (0.0) | 3 (7.2) | 0.08, OR: 11.1
95% CI: (0.51–243.3) |
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OR: odd ratio, CI: confidence interval, No.: number. DSPN No: without DSPN, and DSPN Yes: with DSPN.
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