Research Article

OGG1 Mutations and Risk of Female Breast Cancer: Meta-Analysis and Experimental Data

Figure 2

Superimposed protein structure of mutated OGG1 with its wild type. Wild-type OGG1 protein (grey) and mutated OGG1 protein (blue). Superimposed structure of mutated OGG1 protein showing the location of two observed mutations, Val159Gly and Gly221Arg. Wild-type protein model obtained from protein data bank. Structure was predicted using automated Swiss model. Two structures, wild and mutated, were aligned using UCSF chimera software.