Radiosynthesis, In Vivo Biological Evaluation, and Imaging of Brain Lesions with [123I]-CLINME, a New SPECT Tracer for the Translocator Protein

<div>Synthesis of CLINME and stannane precursor (from bromo) for radiolabelling: (a) for 1, N-methylethylamine, CDI, and THF at 55°C, for 2 N-methylethylamine, EDC, HOBT, in DMF at RT (b) Sn2(Bu)6, Pd(PPh3)4 in toluene at reflux.</div>

Disease Markers

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Figure 2: Radiosynthesis, In Vivo Biological Evaluation, and Imaging of Brain Lesions with [123I]-CLINME, a New SPECT Tracer for the Translocator Protein

Figure 2 | Radiosynthesis, In Vivo Biological Evaluation, and Imaging of Brain Lesions with [123I]-CLINME, a New SPECT Tracer for the Translocator Protein 