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Disease Markers
Volume 2015, Article ID 746329, 7 pages
Research Article

Association of the C47T Polymorphism in SOD2 with Amnestic Mild Cognitive Impairment and Alzheimer’s Disease in Carriers of the APOEε4 Allele

1BIOMICS Research Group, Department of Zoology and Cellular Biology A, Lascaray Research Center (CIEA), University of the Basque Country (UPV/EHU), Vitoria-Gasteiz, 01006 Alava, Spain
2Department of Neurology, Hospital Universitario Cruces, BioCruces Health Research Institute, Barakaldo, 48093 Bizkaia, Spain

Received 12 July 2015; Revised 12 November 2015; Accepted 17 November 2015

Academic Editor: Fabrizia Bamonti

Copyright © 2015 David Gamarra et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

Patients with aMCI were used as the reference category to compute multinomial logistic regression models of rs4880-T (SOD2) and APOEɛ4 allele in AD. As a result, an epistatic effect was found in AD patients in contrast to aMCI patients (Recessive model).

  1. Supplementary Material