Association between BMP4 rs17563 Polymorphism and NSCL/P Risk: A Meta-Analysis

Table 1

Characteristics of case-control studies on BMP4 rs17563 T>C polymorphism and NSCL/P risk included in the meta-analysis.

First author	Year	Country	Racial/descent	Source of controls	Case	Control	Genotype distribution						for HWE^a	Genotyping type	MAF
							Case			Control
							TT	TC	CC	TT	TC	CC
Jianyan et al. [17]	2010	Chinese	Asian	Hospital control	200	200	74	90	36	89	94	17	0.258	PCR-RFLP	0.32
Wang [12]	2012	Chinese	Asian	Hospital control	65	65	21	32	12	32	28	5	0.740	PCR-RFLP	0.29
You [13]	2013	Chinese	Asian	Population control	116	123	40	40	36	46	66	11	0.063	PCR-RFLP	0.36
Araújo [14]	2012	Brazilian	Mixed	Population control	123	246	49	53	21	52	130	64	0.351	PCR-RFLP	0.52
Antunes [15]	2013	Brazilian	Mixed	Hospital control	382	436	176	147	59	150	224	62	0.137	Taqman	0.40
Jin [16]	2013	Chinese	Asian	Hospital control	154	190	66	70	18	104	69	17	0.264	PCR-RFLP	0.27

HWE in control.
MAF: minor allele frequency.