Research Article
Plasma Interleukin-37 Is Elevated in Patients with Rheumatoid Arthritis: Its Correlation with Disease Activity and Th1/Th2/Th17-Related Cytokines
Table 1
Clinical characteristics of the study subjects.
| | Character | Medium (range) | | Inactive RA patients () | Active RA patients
() | Healthy controls () |
| | Age (yrs) | 54 (33–82) | 60 (35–78) | 53 (28–76) | | Gender (male/female) | 4/11 | 1/18 | 6/28 | | Disease duration (yrs) | 6 (0.25–30) | 9 (0.5–27) |
— | | Swollen joint count | 0 (0-0) | 0 (0–20) | — | | Tender joint count | 0 (0-0) | 0 (0–25) | — | | Patient VAS | 30 (10–60) | 70 (30–80) | — | | ESR (mm/h) | 12 (2–21) | 67 (7–110) | — | | CRP (mg/L) | 2.86 (1.07–18.80) | 21.35 (1.85–47.10) | — | |
DAS28 | 2.16 (1.19–2.54) | 5.75 (2.66–8.34) | — | | Remission (DAS28 ≤ 2.6) () | 15 | — | — | | Mild (2.6 < DAS28 ≤ 3.2) () | — | 3 | — | | Moderate (3.2 < DAS28 ≤ 5.1) () | — | 3 | — | | Severe (5.1 < DAS28) () | — | 13 | — |
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DAS28, disease activity score 28; VAS, visual analogue scale; NS, not significant.
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