Research Article

Procalcitonin Improves the Glasgow Prognostic Score for Outcome Prediction in Emergency Patients with Cancer: A Cohort Study

Table 2

Baseline table.

CharacteristicsOverallSurvivorsNonsurvivors value

(%)341 (100%) 260 (76.2%) 81 (23.8%)
Sociodemographics
 Age, years (median, IQR)68 (60, 75)68 (58, 75)69 (61, 75)0.20
 Male gender, (%) 208 (61.0%)162 (62.3%)46 (56.8%)0.37
Diagnosis at ED admission, (%)
 Infection208 (61.0%)152 (58.5%)56 (69.1%)0.016
 Gastrointestinal disease14 (4.1%)12 (4.6%)2 (2.5%)
 Cardiovascular disease42 (12.3%)37 (14.2%)5 (6.2%)
 Worsening of general condition2 (0.6%)2 (0.8%)0 (0.0%)
 Neurological disease50 (14.7%)33 (12.7%)17 (21.0%)
 Other diseases25 (7.3%)24 (9.2%)1 (1.2%)
Main symptom at ED admission, (%)
 General malaise60 (17.8%)40 (15.5%)20 (25.3%)0.46
 Pain48 (14.2%)39 (15.1%)9 (11.4%)
 Gastrointestinal symptom84 (24.9%)65 (25.2%)19 (24.1%)
 Neurological symptom44 (13.1%)36 (14.0%)8 (10.1%)
 Fever55 (16.3%)43 (16.7%)12 (15.2%)
 Respiratory symptom46 (13.6%)35 (13.6%)11 (13.9%)
Primary cancer site, (%)
 Solid cancers276 (80.9%)207 (75%)69 (25%)
  Gastrointestinal tract88 (25.8%)64 (24.6%)24 (29.6%)0.27
  Respiratory tract76 (22.3%)51 (19.6%)25 (30.9%)
  Bones, joints, cartilage6 (1.8%)6 (2.3%)0 (0.0%)
  Skin5 (1.5%)4 (1.5%)1 (1.2%)
  Genital, testis, urogenital58 (17.0%)46 (17.7%)12 (14.8%)
  Brain and nervous system43 (12.6%)36 (13.8%)7 (8.6%)
 Haematological cancers60 (17.6%)49 (81.7%)11 (18.3%)
  Hodgkin’s lymphoma4 (1.2%)4 (1.5%)0 (0.0%)
  Non-Hodgkin’s lymphoma20 (5.9%)17 (6.5%)3 (3.7%)
  Multiple myeloma13 (3.8%)12 (4.6%)1 (1.2%)
  Leukaemia (acute and chronic)23 (6.7%)16 (6.2%)7 (8.6%)
 Not specified or other5 (1.5%)4 (1.5%)1 (1.2%)
Comorbidities, (%)
 Renal failure65 (19.1%)46 (17.7%)19 (23.5%)0.25
 Diabetes mellitus46 (13.5%)36 (13.8%)10 (12.3%)0.73
 COPD32 (9.4%)22 (8.5%)10 (12.3%)0.30
 Coronary heart disease20 (5.9%)16 (6.2%)4 (4.9%)0.68
 Congestive heart failure10 (2.9%)5 (1.9%)5 (6.2%)0.05
Blood biomarkers, median (IQR)
 CRP (mg/L)37.2 (9, 107)28.35 (7.9, 85.9)98 (23.2, 161)<0.001
 Albumin (g/L) 31.7 (26.5, 36.6)33.3 (29, 37.1)26 (21.6, 31.4)<0.001
 WBC (109/L)8.3 (5.4, 11.7)7.9 (5, 11.2)9.2 (6.3, 13.2)0.049
 PCT (μg/L)0.14 (0.08, 0.33)0.13 (0.08, 0.24)0.28 (0.11, 0.69)<0.001
 Urea (mmol/L)6.3 (4.7, 9)6.2 (4.5, 8.7)6.4 (5.3, 11.8)0.062
 25(OH) vitamin D (nmol/L)42.2 (24.6, 61.7)44.9 (27.4, 64)32.2 (19.9, 47.6)<0.001
 Corr Ca (mmol/L)2.39 (2.28, 2.51)2.36 (2.26, 2.46)2.47 (2.35, 2.66)<0.001

WBC: white blood cell count; PCT: procalcitonin; 25(OH) vitamin D: 25-hydroxyvitamin D; corr Ca: corrected calcium; COPD: chronic obstructive pulmonary disease.