Procalcitonin Improves the Glasgow Prognostic Score for Outcome Prediction in Emergency Patients with Cancer: A Cohort Study
Table 5
Biomarkers alone and in combination with GPS for outcome prediction.
Biomarker
Univariate OR (95% CI),
AUC (95% CI)
Adjusted OR (95% CI),
Combined AUC (95% CI)
value (compared to Score)
PCT
1.6 (1.3 to 1.9),
0.69 (0.63 to 0.76)
1.3 (1.1 to 1.6),
0.74 (0.68 to 0.80)
<0.001
25(OH) vitamin D
0.5 (0.3 to 0.8),
0.61 (0.54 to 0.68)
0.6 (0.4 to 0.9),
0.70 (0.64 to 0.77)
0.053
WBC
1.2 (1 to 1.6),
0.57 (0.50 to 0.64)
1.2 (1.0 to 1.6),
0.69 (0.63 to 0.75)
0.21
Urea
1.6 (1 to 2.4),
0.57 (0.50 to 0.64)
1.5 (1.0 to 2.2),
0.71 (0.65 to 0.77)
0.03
Calcium
1604 (69 to 37269),
0.69 (0.62 to 0.75)
158.8 (6.3 to 4022),
0.73 (0.67 to 0.79)
0.002
PCT: procalcitonin; 25(OH) vitamin D: 25-hydroxyvitamin D; WBC: white blood cell count; calcium: corrected calcium. The blood levels of all biomarkers were log-transformed to achieve normality.
