Physical Activity Enhances Metabolic Fitness Independently of Cardiorespiratory Fitness in Marathon Runners

Figure 3

Protein levels as measured by western blot of traditional training markers in runners (solid bars) or pair sedentary controls (open bars) in resting vastus lateralis biopsies. Glutathione peroxidase 1 (a) and manganese superoxide dismutase (MnSOD) (b) were significantly higher in runners (, , 2-way ANOVA). Mitochondrial complex IV (COXIV) (c) was significantly higher in runners (, , 2-way ANOVA). Post hoc significance as determined by Bonferroni corrected -test is indicated by a . Myosin heavy chain IIa (d), vascular endothelial growth factor (VEGF) (e), heat shock protein 70 (HSP70) (f), nor glucose transporter 4 (GLUT4) (g) did not differ between groups. Proteins of interest are normalized to -tubulin as a loading control that did not differ between groups. Representative blots are shown in (h), with C indicating control and R indicating runner.

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