Polymorphisms in C-Reactive Protein and Glypican-5 Are Associated with Lung Cancer Risk and Gartrokine-1 Influences Cisplatin-Based Chemotherapy Response in a Chinese Han Population

Table 4

Relationship between rs2808630 of CRP and lung cancer risk (adjusted by gender and age).

Model	Genotype	Control (, %)	Case (, %)	OR (95% CI)	value	value adj.	AIC	BIC
Codominant	T/T	189 (65.4%)	218 (75.4%)	1.00	0.100	0.500	710.2	732.0
	T/C	90 (31.1%)	64 (22.1%)	0.64 (0.43–0.97)
	C/C	10 (3.5%)	7 (2.4%)	0.80 (0.28–2.30)
Dominant	T/T	189 (65.4%)	218 (75.4%)	1.00	0.036	0.180	708.3	725.8
	T/C-C/C	100 (34.6%)	71 (24.6%)	0.66 (0.44–0.98)
Recessive	T/T-T/C	279 (96.5%)	282 (97.6%)	1.00	0.850	1	712.7	730.1
	C/C	10 (3.5%)	7 (2.4%)	0.90 (0.32–2.58)
Overdominant	T/T-C/C	199 (68.9%)	225 (77.8%)	1.00	0.037	0.185	708.3	725.8
	T/C	90 (31.1%)	64 (22.1%)	0.65 (0.43–0.98)
Log-additive				0.72 (0.51–1.02)	0.061	0.305	709.2	726.6

AIC: Akaike's information criterion; BIC: Bayesian information criterion.
value was adjusted by Bonferroni correction.