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Disease Markers
Volume 2015 (2015), Article ID 825435, 4 pages
Research Article

Aldehyde Dehydrogenase Polymorphisms and Blood Pressure Elevation in the Japanese: A Cross-Sectional and a Longitudinal Study over 20 Years in the Shimane CoHRE Study

1Department of Functional Pathology, Shimane University, Izumo 693-8501, Japan
2The Center for Community-Based Health Research and Education (CoHRE), Shimane University, Izumo 693-8501, Japan
3Department of Environmental and Preventive Medicine, School of Medicine, Shimane University, Izumo 693-8501, Japan

Received 2 April 2015; Revised 2 June 2015; Accepted 9 June 2015

Academic Editor: George Perry

Copyright © 2015 Minoru Isomura et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

Table S1. The risk of the ALDH2 gene polymorphism on hypertension was examined separately by drinking status. These analyses revealed that the ALDH2 polymorphism was a risk factor for hypertension even in non-habitual drinkers.

Table S2. Multivariate linear regression analysis on factors influencing ΔSBP in the longitudinal study showed that that only ΔBMI in men showed a significant association with ΔSBP.

  1. Supplementary Material