MHC Class I Chain-Related Gene A Diversity in Patients with Cutaneous Malignant Melanoma from Southeastern Spain

Table 2

Allelic frequency of MICA gene in melanoma patients and controls.

Allele	Controls; (%)	Melanoma patients; (%)	P/Pc value
MICA^*001	24 (12)	38 (16)
MICA^*002	57 (28)	39 (17)	0.004/0.07
MICA^*004	52 (26)	77 (33)
MICA^*005	1 (0.5)	0 (0)
MICA^*006	1 (0.5)	0 (0)
MICA^*007	12 (6)	14 (6)
MICA^*008	105 (52)	117 (50)
MICA^*009	29 (14)	62 (27)	0.002/0.03
MICA^*010	12 (6)	4 (2)	0.022/0.37
MICA^*011	17 (8)	23 (10)
MICA^*012	5 (2)	7 (3)
MICA^*015	7 (3)	2 (1)
MICA^*016	14 (7)	26 (11)
MICA^*017	6 (3)	11 (5)
MICA^*018	11 (5)	17 (7)
MICA^*019	8 (4)	1 (0.4)	0.014/0.24
MICA^*027	2 (1)	0 (0)

MICA, major histocompatibility complex class I chain-related gene A. P value was determined by two-sided Fisher’s exact test. Note. Valine 129 positive alleles: MICA^*004, ^*005, ^*006, ^*008, ^*009, ^*010, ^*016, ^*019, ^*027; methionine 129 positive alleles: MICA^*001, ^*002, ^*007, ^*011, ^*012, ^*015, ^*017, ^*018.