Research Article

MHC Class I Chain-Related Gene A Diversity in Patients with Cutaneous Malignant Melanoma from Southeastern Spain

Table 5

MICA-129 allele and genotype frequencies in melanoma patients and controls.

MICA-129 polymorphismControls 

(%)
Melanoma patients 

(%)
P value

Alleles
 Val129177 (88)209 (90)0.76
 Met129122 (61)131 (56)0.33
Genotypes
 Val/Val12978 (39)102 (44)0.33
 Met/Val12999 (49)107 (46)0.50
 Met/Met12923 (12)24 (10)0.76

MICA: major Histocompatibility complex class I chain-related gene A. P value for disease susceptibility was determined by two-sided Fisher’s exact test.
Note. Valine 129 (Val129) positive alleles: MICA*004, *005, *006, *008, *009, *010, *016, *019, *027; methionine 129 (Met129) positive alleles: MICA*001, *002, *007, *011, *012, *015, *017, *018.