Aerobic Glycolysis as a Marker of Tumor Aggressiveness: Preliminary Data in High Grade Human Brain Tumors

Figure 2

Coregistered PET and MR images from an individual with PNET WHO stage IV (participant #6). Red line delineates the area with the largest increase in AG. ((a)–(c)) MR and PET images at the time of the PET study and 1 day before surgery: (a) T1-weighted image with contrast (Gadolinium) enhancement; (b) CMRGlu PET image; (c) AG PET image. ((d)–(f)) T1-weighted MR images with contrast (Gadolinium) enhancement after partial surgical resection: (d) five days and (e) six weeks after surgery; (f) five months after surgery followed by radiation and chemotherapy.

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