Metabolic Serum Profiles for Patients Receiving Allogeneic Stem Cell Transplantation: The Pretransplant Profile Differs for Patients with and without Posttransplant Capillary Leak Syndrome

Figure 1

Random forest analysis of pretransplant metabolite levels: identification of metabolites showing altered serum levels in patient with capillary leak syndrome. Random forest analysis could distinguish between the metabolic signatures of patients with and without capillary leak syndrome with a predictive accuracy of 62%, suggesting that these metabolites are candidate biomarkers for increased risk of capillary leak syndrome. The figure presents the top 30 metabolites based on their importance to separate the two patient groups. The different colors reflect the metabolite classification as indicated at the bottom of the figure.