Procalcitonin, MR-Proadrenomedullin, and Cytokines Measurement in Sepsis Diagnosis: Advantages from Test Combination

Table 1

Demographic characteristics of the sepsis patients, SIRS patients, and the healthy individuals included in the study population.

Sepsis patients
Number of patients	104
Mean age	66 ± 12
Male	59
Female	45
Sepsis	63
Gram-positive	26
Gram-negative	34
Yeast	3
Severe sepsis/septic shock	41
Gram-positive	15
Gram- negative	19
Yeast	7
APACHE II score
Sepsis 16.2 (surv.: 15.4; nonsurv.: 20.2)
Severe sepsis 19.6 (surv.: 18.5; nonsurv.: 20.7)
SOFA score
Sepsis 3.6 (surv.: 2.6; nonsurv.: 5.2)
Severe sepsis 6.3 (surv.: 5; nonsurv.: 7)
With comorbidities
Diabetes	8
Malignancy	48
Hematological malignancies	13
Cardiovascular disease	10
Gastrointestinal disease	6
Autoimmune disease	4
Renal failure	5
Others	12
Site of primary infection
Pneumoniae	9
Intra-abdominal	29
Urinary tract infection	20
CVC colonization	14
Soft tissue	11
Unknown	21
SIRS patients
Number of patients	51
Mean age	60 ± 10
Male	27
Female	24
APACHE II score
7.9 (surv.: 7.1; nonsurv.: 9.6)
With comorbidities
Diabetes	2
Malignancy	15
Hematological malignancies	36
Cardiovascular disease	2
Gastrointestinal disease	4
Autoimmune disease	2
Hepatic failure	1
Others	4
Healthy controls
Number of patients	50
Mean age	65 ± 12
Male	35
Female	15

surv.: survivor; nonsurv.: nonsurvivor.