Procalcitonin, MR-Proadrenomedullin, and Cytokines Measurement in Sepsis Diagnosis: Advantages from Test Combination

Table 6

Receiver operating characteristic (ROC) curves: areas under the curves (AUCs) characteristics and cutoff values for APACHE II and SOFA scores in all sepsis (sepsis + SS), sepsis, and SS patients.

	APACHE II				SOFA
	All sepsis versus SIRS	Sepsis versus SIRS	SS versus SIRS	SS versus sepsis	SS versus sepsis
AUC	0.93	0.91	0.98	0.82	0.91
Sensitivity %	83	75	95	95	91
Specificity %	99	99	99	58	80
LR+	3.64	3.31	4.15	2.31	4.55
Cutoff value	12	12	12	12	4

SS, severe sepsis/septic shock patients; SIRS, systemic inflammatory response syndrome.