Procalcitonin, MR-Proadrenomedullin, and Cytokines Measurement in Sepsis Diagnosis: Advantages from Test Combination

Table 7

Multiple logistic regression analysis: sepsis versus PCT, MR-proADM, IL-6, IL-10, TNF-α, and MCP-1 (variables were included if and removed if ). (A) The group of sepsis patients (104 subjects) were compared with SIRS patients and healthy individuals (101 subjects). (B) Sepsis patients (104 subjects) were compared only with SIRS patients (51 subjects).

Independent variable	OR	95% CI	value
(A) Sepsis: dependent variable
PCT	12.6136	1.7315 to 91.8885	0.0124
MR-proADM	25.8435	6.9528 to 96.0593	<0.0001
IL-6	7.2262	2.0087 to 25.9954	0.0025
TNF-α	4.8752	1.3204 to 18.0004	0.0175
(B) Sepsis: dependent variable
PCT	9.4602	1.5411 to 58.0723	0.0152
MR-proADM	23.3066	5.9188 to 91.7756	<0.0001
TNF-α	10.4546	2.7075 to 40.3693	0.0007