Research Article
High CD133 Expression in the Nucleus and Cytoplasm Predicts Poor Prognosis in Non-Small Cell Lung Cancer
Table 2
Univariate and multivariate analysis of prognostic factors in NSCLC for 5-year overall survival.
| Variable | Years | Univariate analysis | Multivariate analysis | value | HR | value | 95% CI |
| CD133 expression in cytoplasm | High versus low | 5 | <.001* | 2.709 | <.001* | 1.898 | 3.866 |
| CD133 expression in nuclear | High versus low | 5 | <.001* | 5.211 | <.001* | 3.525 | 7.703 |
| Gender | Male versus female | 5 | .655 | | | | |
| Age (years) | ≤60 versus >60 | 5 | .165 | | | | |
| Tumor diameter (cm) | ≤4 versus >4 | 5 | .035* | 1.52 | .005* | 1.138 | 2.051 |
| Histological type | Sq versus Ad versus SA | 5 | .300 | | | | |
| Differentiation | Well versus moderate versus poor | 5 | .001* | 1.393 | .015* | 1.066 | 1.820 |
| Stage | I versus II versus III-IV | 5 | .027* | | | | |
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