High CD133 Expression in the Nucleus and Cytoplasm Predicts Poor Prognosis in Non-Small Cell Lung Cancer

Table 2

Univariate and multivariate analysis of prognostic factors in NSCLC for 5-year overall survival.

Variable	Years	Univariate analysis	Multivariate analysis
		value	HR	value	95% CI
CD133 expression in cytoplasm
High versus low	5	<.001^*	2.709	<.001^*	1.898	3.866
CD133 expression in nuclear
High versus low	5	<.001^*	5.211	<.001^*	3.525	7.703
Gender
Male versus female	5	.655
Age (years)
≤60 versus >60	5	.165
Tumor diameter (cm)
≤4 versus >4	5	.035^*	1.52	.005^*	1.138	2.051
Histological type
Sq versus Ad versus SA	5	.300
Differentiation
Well versus moderate versus poor	5	.001^*	1.393	.015^*	1.066	1.820
Stage
I versus II versus III-IV	5	.027^*

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