IL-4 Gene Polymorphism May Contribute to an Increased Risk of Atopic Dermatitis in Children

Table 3

Allele and genotype frequency distribution of IL-4 single nucleotide polymorphisms, 590C/T and 589C/T, in the case group and the control group.

	Case group ()	Control group ()		OR (95% CI)
590C/T
CC	3	6		Ref.
CT	17	33		1.03 (0.23–4.64)
TT	62	61	0.111	3.03 (0.49–8.50)
CT + TT	79	94		1.68 (0.41–6.94)
C	23	45		Ref.
T	141	155	0.039	1.78 (1.03–3.09)
589C/T
CC	1	3		Ref.
CT	15	36		1.25 (0.12–13.01)
TT	66	61	0.017	3.25 (0.33–32.06)
CT + TT	81	97		2.51 (0.256–24.56)
C	17	42		Ref.
T	147	158	0.007	2.30 (1.25–4.22)

Note: Ref., reference; OR, odd ratio; 95% CI, 95% confidence intervals.