IL-4 Gene Polymorphism May Contribute to an Increased Risk of Atopic Dermatitis in Children

Table 7

Association of the severity of AD with serum IL-4 level of IL-4 single nucleotide polymorphisms, 590C/T and 589C/T.

	Genotypes	Control group	Mild group ()	Moderate group ()	Severe group ()
590C/T	CC	36.4 ± 7.3	—	37.2	37.3 ± 12.9
	CT	37.9 ± 6.2	49.3 ± 10.6	77.2 ± 12.0	96.6 ± 9.9
	TT	39.3 ± 8.9	52.2 ± 8.7	90.7 ± 16.3	117.4 ± 13.1
589C/T	CC	22.11 ± 2.6	—	—	89.26
	CT	31.52 ± 3.07	42.85 ± 2.88	61.04 ± 10.72	95.53
	TT	43.69 ± 5.44	58.06 ± 6.71	91.19 ± 14.65	108.30 ± 27.66

Note: , compared with the control group; , compared with the mild group; , compared with the moderate group; , compared with the wild homozygote; , compared with the heterozygote.