Research Article

The Correlation of Serums CCL11, CCL17, CCL26, and CCL27 and Disease Severity in Patients with Urticaria

Table 1

General characteristic of AU, CSU, and control groups.

VariablesAU ()CSU ()Control ()

Age (year)28.00 (22.25–42.00)31.50 (26.00–53.75)43.00 (34.50–51.25)
Gender (male/female)6/225/1912/13
CCL27 (pg/mL)1281.23 (987.27–2069.86)754.94 (516.88–1659.07)976.54 (724.25–1142.84)
CCL11 (pg/mL)17.56 (11.85–33.11)22.70 (15.86–28.21)12.84 (9.00–17.78)♦ΔΔ
CCL26 (pg/mL)11.91 (3.72–24.18)4.57 (2.45–11.16)2.00 (1.74–2.34)♦♦ΔΔ
CCL17 (pg/mL)159.92 (86.84–722.18)67.55 (33.19–241.44)21.29 (16.37–34.62)♦♦ΔΔ
D-dimer (ug/L)4550.00 (1122.50–6955.00)1105.00 (642.50–5017.50)245.00 (160.00–487.50)♦♦ΔΔ
IgE (ng/mL)530.88 (309.91–746.35)442.22 (372.18–548.56)440.70 (379.15–605.16)
IgG (g/L)10.47 (9.89–11.05)11.80 (11.10–12.50)11.56 (7.51–15.60)
IgA (g/L)1.97 (1.79–2.15)2.14 (1.94–2.34)2.68 (0.82–4.53)
IgM (g/L)1.12 (1.02–1.22)1.51 (1.31–1.71)1.75 (0.46–3.04)
C3 (g/L)0.89 (0.84–0.94)0.99 (0.92–1.06)1.16 (0.79–1.52)
C4 (g/L)0.19 (0.17–0.21)0.21 (0.19–0.23)0.27 (0.16–0.38)
ESR (mm/h)16.00 (13.30–18.70)12.46 (9.83–15.10)7.50 (0.50–15.00)
WBC (/L)11.05 (8.52–13.31)7.53 (6.15–9.06)6.90 (6.15–7.63)♦♦
Eo (/L)0.06 (0.02–0.16)0.09 (0.04–0.15)0.16 (0.09–0.28)♦♦Δ
RBC (/L)4.40 (4.04–4.62)4.44 (4.16–4.93)4.74 (4.52–5.26)♦♦
Hb (g/L)126.00 (116.25–135.50)131.00 (125.50–140.75)142.50 (133.00–152.50)♦♦Δ
PLT (/L)250.50 (193.25–305.25)245.50 (226.50–319.75)239.50 (217.75–261.50)Δ
Glu (mmol/L)5.41 (4.74–5.64)5.27 (4.89–5.64)5.15 (5.03–5.36)
CRP (mg/L)29.86 (15.85–43.87)12.83 (6.01–19.65)4.00 (0.01–8.00)♦Δ

CCL, chemokine ligand; Ig, immunoglobulin; C3, complement 3; C4, complement 4; ESR, erythrocyte sedimentation rate; WBC, white blood cell; Eo, eosinophil; RBC, red blood cell; PLT, platelet; Glu, glucose; CRP, C-reactive protein; AU, acute urticaria; CSU, chronic spontaneous urticaria.
and when AU group was compared with CSU group.
and when AU group was compared with the control.
and when CSU group was compared with the control.