Two tagSNPs rs352493 and rs3760908 within SIRT6 Gene Are Associated with the Severity of Coronary Artery Disease in a Chinese Han Population

Table 1

The characteristics of CAD cases and controls.

Variable	Controls ()	Cases ()
Age (years)	61.50 ± 12.50	63.19 ± 11.68	0.021
Sex (male)	379 (57.9%)	362 (76.4%)	<0.001
Smoking	154 (23.5%)	286 (60.3%)	<0.001
Alcohol consumption	99 (15.1%)	123 (25.9%)	<0.001
Hypertension	221 (33.7%)	293 (61.8%)	<0.001
Diabetes	104 (15.9%)	229 (48.3%)	<0.001
Hyperlipidemia	239 (36.5%)	314 (66.2%)	<0.001
Systolic BP (mm Hg)	131.83 ± 19.38	139.70 ± 19.80	<0.001
Diastolic BP (mm Hg)	72.78 ± 10.63	73.42 ± 11.24	0.332
FPG (mM)	5.79 ± 1.95	6.27 ± 1.64	<0.001
Triglycerides (mM)	1.48 ± 0.81	1.90 ± 1.09	<0.001
Total cholesterol (mM)	4.59 ± 1.15	4.67 ± 1.21	0.266
HDL cholesterol (mM)	1.39 ± 0.67	1.24 ± 0.44	<0.001
LDL cholesterol (mM)	2.61 ± 0.92	2.88 ± 0.92	<0.001

Two-sided chi-square test or independent-samples -test.
values under 0.05 were indicated in bold font.