Expression of Cancer Testis Antigens in Colorectal Cancer: New Prognostic and Therapeutic Implications
Table 2
Comparison between CTA expressions in normal and cancer tissue obtained during colonoscopy.
CTA
Median
IQR
value
Cancer versus normal
MAGEA1
1.004268
3.557637
0.923
MAGEA2
1.068458
2.669421
0.586
MAGEA3
1.488304
1.660176
0.003
OIP5
2.520143
2.942988
SSX4
1.70662
4.9859
0.365
PLAC1
1.467123
2.930341
0.072
CAGE1
1.183878
2.159953
0.188
TTK
3.512544
4.599179
CXorf48
1.000834
6.828382
0.538
KU-CT-1
2.57151
16.58306
0.128
HAGE
1.139154
3.847637
0.177
PLU1
1.178954
0.914003
0.018
LDHC
1.559463
8.283443
0.232
NY-ESO-1
1.443452
4.199511
0.604
DKKL
1.365828
2.845266
0.040
FBXO39
2.136684
1.850426
RGS22
0.485704
1.391908
0.251
CAGE
1.041833
2.008881
0.879
RNA was isolated from cancer tissue and normal tissue located ~5 cm away and reverse transcribed and CTA expression was analyzed by real-time PCR. Differences with value <0.05 (Wilcoxon signed-rank test) are in bold font.