Expression of Cancer Testis Antigens in Colorectal Cancer: New Prognostic and Therapeutic Implications

Table 2

Comparison between CTA expressions in normal and cancer tissue obtained during colonoscopy.

	CTA	Median	IQR	value
Cancer versus normal	MAGEA1	1.004268	3.557637	0.923
	MAGEA2	1.068458	2.669421	0.586
	MAGEA3	1.488304	1.660176	0.003
	OIP5	2.520143	2.942988
	SSX4	1.70662	4.9859	0.365
	PLAC1	1.467123	2.930341	0.072
	CAGE1	1.183878	2.159953	0.188
	TTK	3.512544	4.599179
	CXorf48	1.000834	6.828382	0.538
	KU-CT-1	2.57151	16.58306	0.128
	HAGE	1.139154	3.847637	0.177
	PLU1	1.178954	0.914003	0.018
	LDHC	1.559463	8.283443	0.232
	NY-ESO-1	1.443452	4.199511	0.604
	DKKL	1.365828	2.845266	0.040
	FBXO39	2.136684	1.850426
	RGS22	0.485704	1.391908	0.251
	CAGE	1.041833	2.008881	0.879

RNA was isolated from cancer tissue and normal tissue located ~5 cm away and reverse transcribed and CTA expression was analyzed by real-time PCR. Differences with value <0.05 (Wilcoxon signed-rank test) are in bold font.