Expression of Cancer Testis Antigens in Colorectal Cancer: New Prognostic and Therapeutic Implications

Table 3

Analysis of CTA expression in relation to disease progression (Dukes staging in CRC).

Variable	CTA	RE		AE
		value	value	value	value
Staging	MAGEA1	0.14	0.417	0.04	0.800
	MAGEA2	0.40	0.017	0.13	0.408
	MAGEA3	0.15	0.254	0.33	0.039
	OIP5	0.28	0.086	0.01	0.957
	SSX4	0.18	0.276	0.16	0.336
	PLAC1	0.19	0.240	0.34	0.034
	CAGE1	0.19	0.235	0.25	0.122
	TTK	0.05	0.750	0.25	0.116
	CXorf48	0.28	0.082	0.30	0.080
	KU-CT-1	0.26	0.102	0.22	0.195
	HAGE		0.402		0.373
	PLU-1	0.46	0.003	0.07	0.680
	LDHC		0.195	0.32	0.071
	NY-ESO-1	0.31	0.051	0.05	0.777
	DKKL	0.14	0.391	0.33	0.037
	FBXO39		0.818	0.04	0.812
	RGS22	0.40	0.015	0.23	0.145
	CAGE	0.08	0.635	0.21	0.200

The Spearman rank correlation coefficient was used to analyze the correlation between the stage and CTA expression level in cancer tissue. Both relative expression (RE) and absolute expression (AE) were calculated. Correlations with value <0.05 are in bold font.