Expression of Cancer Testis Antigens in Colorectal Cancer: New Prognostic and Therapeutic Implications

Table 4

Analysis of CTA expression in relation to disease progression.

Variable	CTA	Median CD	Median AB	RE value
Staging C + D versus A + B	MAGEA1	1.183	0.820	0.188
	MAGEA2	2.220	0.706	0.009
	MAGEA3	1.881	1.488	0.085
	OIP5	3.168	2.114	0.034
	SSX4	2.313	0.959	0.350
	PLAC1	2.702	1.050	0.336
	CAGE1	2.498	1.034	0.144
	TTK	4.756	3.378	0.101
	CXorf48	1.817	0.797	0.058
	KU-CT-1	3.569	1.633	0.605
	HAGE	1.139	0.929	0.560
	PLU-1	1.659	0.939	0.044
	LDHC	2.004	0.794	0.157
	NY-ESO-1	2.946	0.827	0.129
	DKKL	1.844	1.184	0.382
	FBXO39	2.204	1.877	0.517
	RGS22	0.877	0.353	0.159
	CAGE	1.305	0.703	0.424

Mann-Whitney test was applied to compare late stages C + D with stages A and B. Correlations with value <0.05 are in bold font.