Postnatal Changes in Humerus Cortical Bone Thickness Reflect the Development of Metabolic Bone Disease in Preterm Infants

Table 3

Comparison of the serum and urinary biochemical data of preterm infants with and without decreasing cortical bone thickness at 36–44 weeks of postmenstrual age.

Characteristic	Decreasing cortical; bone thickness; ()	Nondecreasing; cortical bone thickness; ()	p value
Serum Ca level (mg/dL)	9.7 (9.3–10.1)	9.6 (9.0–10.7)	0.80
Serum P level (mg/dL)	5.9 (4.7–6.0)	5.8 (4.8–6.6)	0.97
Urinary Ca/Cr level (mg/mg)	0.3 (0.1–0.6)	0.4 (0.1–1.3)	0.46
Urinary P/Cr level (mg/mg)	1.6 (0.2–2.5)	0.5 (0.0–1.3)	0.03
TRP (%)	94.4 (85.0–99.0)	98 (90–100)	0.07
ALP (U/L)	1676 (1265–2692)	1036 (679–1877)	<0.01

ALP, alkaline phosphatase; Ca, calcium; Cr, creatinine; P, phosphorus; PMA, postmenstrual age; TRP, tubular reabsorption of phosphate. Values are expressed as median (range) or number (%).