Pilot Study on MAGE-C2 as a Potential Biomarker for Triple-Negative Breast Cancer

Table 2

Univariate and multivariate analysis of disease-free survival in 110 patients.

Variables	Univariate			Multivariate
	HR	95% CI	value	HR	95% CI	value
Age, years (≤35 versus >35)	0.408	0.202–0.821	0.012	0.367	0.174–0.773	0.008
Tumor size, cm (≤2 versus >2)	1.551	0.640–3.757	0.331	1.381	0.528–3.609	0.510
Lymph node status (negative versus positive)	5.096	2.207–11.768	<0.001	3.274	1.229–8.723	0.018
TNM stage (I/II versus II)	2.975	1.498–5.909	0.002	1.574	0.547–4.528	0.400
Differentiation (well versus moderate/poor)	4.346	0.594–31.816	0.148	2.720	0.325–22.744	0.356
Lymphovascular invasion (no versus yes)	4.490	2.257–8.931	<0.001	2.803	1.087–7.225	0.033
MAGE-C2 expression (low versus high)	2.170	1.092–4.311	0.027	1.513	1.168–3.567	0.041