Pilot Study on MAGE-C2 as a Potential Biomarker for Triple-Negative Breast Cancer

Table 3

Univariate and multivariate analysis of overall survival in 110 patients.

Variables	Univariate			Multivariate
	HR	95% CI	value	HR	95% CI	value
Age, years (≤35 versus >35)	0.366	0.173–0.775	0.009	0.353	0.160–0.779	0.010
Tumor size, cm (≤2 versus >2)	1.565	0.595–4.118	0.364	1.392	0.491–3.945	0.534
Lymph node status (negative versus positive)	4.946	2.002–12.219	0.001	2.733	1.947–7.887	0.043
TNM stage (I/II versus III)	3.287	1.558–6.935	0.002	1.476	0.468–4.654	0.507
Differentiation (well versus moderate/poor)	3.595	0.488–26.465	0.209	2.413	0.280–20.766	0.423
Lymphovascular invasion (no versus yes)	4.875	2.310–10.287	<0.001	2.730	1.964–7.725	0.049
MAGE-C2 expression (low versus high)	2.517	1.189–5.329	0.016	0.726	0.229–2.299	0.586