TBL1XR1 Is Highly Expressed in Gastric Cancer and Predicts Poor Prognosis

Table 2

Univariate and multivariate analysis of different prognostic factors for overall survival of patients with gastric cancer.

Variable	All cases	Univariate analysis		Multivariate analysis
		Mean ± SE	value	HR	95% CI	value
Gender
Male	233	35.66 ± 1.87	0.053
Female	101	28.83 ± 2.59
Age at surgery
<57	172	32.34 ± 2.14	0.312
≥57	162	35.16 ± 2.20
Tumor size
≥5 cm	149	31.42 ± 2.21	0.289
<5 cm	185	35.35 ± 2.11
Histological type
Intestinal	265	35.04 ± 1.68	0.006	1.507	1.004–2.262	0.048
Diffuse	69	24.81 ± 3.22
TNM
I + II	117	52.14 ± 2.15	0.000	1.862	1.348–2.573	0.000
III + IV	217	24.73 ± 1.64
Lymph node metastases
Present	234	25.73 ± 1.61	0.003	0.286	0.139–0.590	0.001
Absent	100	54.34 ± 1.53
TBL1XR1 protein expression
High	204	28.99 ± 1.86	0.000	0.525	0.367–0.752	0.005
Low	130	41.53 ± 2.48

SE, standard error; Chi-square test; HR, hazard ratio; CI, confidence interval; median age.