Identification of Differentially Expressed Kinase and Screening Potential Anticancer Drugs in Papillary Thyroid Carcinoma

Table 2

Potential novel kinase inhibitors for the treatment of PTC.

Kinase	Kinase inhibitor	Publication number
EGFR	Gefitinib (ZD1839)	3040
	Erlotinib HCl (OSI-744)	4310
	Lapatinib	1681
	Afatinib (BIBW2992)	409
	AZD8931 (Sapitinib)	389
	AG-1478 (Tyrphostin AG-1478)	273
	AG-490 (Tyrphostin B42)	221
	PD153035 HCl	136
	Neratinib (HKI-272)	113
	Canertinib (CI-1033)	94
	Icotinib	69
	AEE788 (NVP-AEE788)	61
	Pelitinib (EKB-569)	43
	Varlitinib	32
	OSI-420	31
	PD168393	24
	Rociletinib (CO-1686, AVL-301)	23
	WZ4002	18
	WHI-P154	15
	CUDC-101	13
	TAK-285	12
	Tyrphostin 9	8
	AST-1306	5
	CL-387785 (EKI-785)	5
	AG-18	2
SRC	Dasatinib	1771
	PP2	345
	Bosutinib (SKI-606)	207
	Saracatinib (AZD0530)	126
	SU6656	64
	KX2-391	8
	NVP-BHG712	2
	Dasatinib Monohydrate	2
MAPK	BMS-536924	29
MET	SU11274	98
	Foretinib (GSK1363089)	26
	SGX-523	7
	NPS-1034	2
	NVP-BVU972	2
ATM	AZD8055	66
	KU-55933 (ATM Kinase Inhibitor)	42
	KU-60019	9
CDK6	Flavopiridol (Alvocidib) HCl	374
	PD-0332991	137
	LY2835219	9
	LDC000067	1
TGFbR1	SB431542	114
	SD-208	25
	SB505124	10
	EW-7197	8
	SB525334	6
	D 4476	2
	RepSox	1
	GW788388	1
PDGFRa	Imatinib (STI571)	6749
	Ponatinib (AP24534)	192
	Nintedanib (BIBF 1120)	102
	Masitinib (AB1010)	52
	Lenvatinib (E7080)	28
	Quizartinib (AC220)	24
	Crenolanib (CP-868596)	19
	Amuvatinib (MP-470)	13
	ENMD-2076	12
	Telatinib	11
	OSI-930	8
	CP-673451	5
ErbB4	AZD8931 (Sapitinib)	12