WISP1 Is Increased in Intestinal Mucosa and Contributes to Inflammatory Cascades in Inflammatory Bowel Disease

Figure 4

WISP1 was upregulated in TNBS-induced colitis. (a) WISP1 mRNA relative expression was determined in colonic samples from ethanol-treated mice () and TNBS-treated mice () by (qRT-)PCR. (b) Western blot analysis of WISP1 expression in total proteins from colonic samples from ethanol-treated mice () and TNBS-treated mice (). Lower panel in (b) shows the quantitative analysis of WISP1/β-actin ratio. (c) Representative western blot analysis of WISP1 expression in total proteins from colonic samples from ethanol-treated mice and TNBS-treated mice at days 2, 4, and 6 after colitis induction, respectively. Representative results from three independent experiments are shown. Student’s -test was performed. data are expressed as mean ± s.e.m. for all samples.

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