Disease Markers

Research Article

Toward Noninvasive Diagnosis of IgA Nephropathy: A Pilot Urinary Metabolomic and Proteomic Study

Table 3

Selected reaction monitoring transitions of compounds derivatized with Girard’s reagent T.


Analyte	SRM transition	CID energy [eV]

Hexanal		16
Heptanal		16
Oktanal		16
Nonanal		16
Decanal		16
Undecanal		16
Dodecanal		17
Malondialdehyde		8
4-Hydroxynonenal		15
4-Hydroxyhexenal		15
8-Isoprostane-PGF_2α		15
Leukotriene B₄		17
Leukotriene C₄		14
Leukotriene D₄		15
Leukotriene E₄		15

Q1, precursor ion; Q3, product ion; SRM, selected reaction monitoring; CID, collision-induced dissociation; Girard’s reagent T, (carboxymethyl) trimethylammonium chloride hydrazide.