Disease Markers / 2016 / Article / Tab 4

Research Article

Interplay between Matrix Metalloproteinase-9, Matrix Metalloproteinase-2, and Interleukins in Multiple Sclerosis Patients

Table 4

Percentage of MS patients and OND controls with abnormal serum and CSF values.

OND (%)MS (%)

Serum
 High active MMP-946.753.9
 Low active MMP-253.349.4
 High IL-178.712.4
 High IL-1843.542.7
 High IL-2332.638.2
 High MCP-330.430.3
Combined interleukins63.069.7

CSF
 High active MMP-940.262.9
 Low active MMP-251.847.6
 High IL-1720.713.5
 High IL-1828.330.3
 High IL-239.89.0
 High MCP-328.324.7
Combined interleukins45.744.9

The cut-off values used for the determination of the frequency of abnormal values were as follows.
Serum: active MMP-9, 534 ng/mL; active MMP-2, 25.2 ng/mL; IL-17, 33.6 pg/mL; IL-18, 2262 pg/mL; IL-23, 181 pg/mL; MCP-3, 7.2 pg/mL.
CSF: active MMP-9, 0.055 ng/mL; active MMP-2, 5.06 ng/mL; IL-17, 7 pg/mL; IL-18, 237 pg/mL; IL-23, 15.9 pg/mL; MCP-3, 3 pg/mL.
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