Expression of CAF-Related Proteins Is Associated with Histologic Grade of Breast Phyllodes Tumor

Table 6

Multivariate analysis of disease-free and overall survival in patients with phyllodes tumors.

Included factor	Disease-free survival			Overall survival
	Hazard ratio	95% CI	value	Hazard ratio	95% CI	value
Histologic grade			0.002			N/A
Benign versus borderline/malignant	7.990	2.196–29.07		N/A	N/A
Stromal cellularity			0.597			0.467
Mild versus moderate/marked	0.625	0.109–3.569		2.862	0.169–48.60
Stromal atypia			0.886			0.708
Mild versus moderate/marked	0.881	0.158–4.925		0.630	0.056–7.049
Stromal mitosis			0.854			0.437
0–4/10 HPF versus >4/10 HPF	0.782	0.057–10.81		0.210	0.004–10.70
Stromal overgrowth			0.029			0.006
Absent versus present	7.288	1.225–43.35		58.10	3.116–1083
Tumor margin			0.275			0.187
Circumscribed versus infiltrative	0.468	0.120–1.830		0.321	0.060–1.732
PDGFRα (stromal)			0.867			0.050
Negative versus positive	0.879	0.193–4.008		5.486	1.003–30.01

HPF, high-power field.