Tumor Necrosis Factor-α T-857C (rs1799724) Polymorphism and Risk of Cancers: A Meta-Analysis
Table 1
Characteristics of published studies included in this meta-analysis.
First author
Country
Ethnicity
Cancer type
Sample size
Control source
Case
Control
Methods
HWE
de Oliveira 2015
Brazilian
Caucasian
Gastric cancer
262/240
HB
157/95/10
157/64/19
PCR-RFLP
<0.01
Yang 2009
Korean
Asian
Gastric cancer
84/325
PB
49/33/2
227/92/6
PCR
0.34
Hou 2007
Poland
Caucasian
Gastric cancer
304/416
PB
226/74/4
312/99/5
TaqMan
0.36
Sugimoto 2007
Japanese
Asian
Gastric cancer
105/172
HB
66/27/12
125/40/7
PCR-RFLP
0.11
Shirai 2006
Japanese
Asian
Gastric cancer
168/479
PB
102/62/4
316/146/17
TaqMan
0.98
Zambon 2005
Italian
Caucasian
Gastric cancer
129/644
HB
83/44/2
404/227/13
PCR-RFLP
<0.01
Wu 2004
Chinese
Asian
Gastric cancer
204/210
PB
148/51/5
152/56/2
PCR
0.20
Ohyama 2004
Japanese
Asian
Gastric cancer
300/472
HB
193/98/9
312/144/16
TaqMan
0.90
Lee 2004
Korean
Asian
Gastric cancer
341/261
PB
229/97/15
185/69/7
PCR
0.85
Hamadien 2016
Arabian
African
Colorectal cancer
100/100
HB
85/15/0
85/15/0
TaqMan
0.42
Kapitanović 2014
Croatian
African
Colorectal cancer
200/200
PB
130/64/6
126/67/7
TaqMan
0.60
Garrity-Park 2008
American
Caucasian
Colorectal cancer
114/114
HB
98/16/0
92/22/0
PCR
0.25
Landi 2006
Spanish
Caucasian
Colorectal cancer
281/268
HB
219/58/4
220/45/3
TaqMan
0.68
Yang 2015
Chinese
Asian
HCC
298/889
HB
203/79/16
622/228/39
PCR-RFLP
<0.01
Shin 2015
Korean
Asian
HCC
157/201
PB
116/35/6
142/53/6
PCR–RFLP
0.70
Jung 2009
Korean
Asian
HCC
227/ 365
HB
137/75/15
258/100/7
PCR
0.45
Wang 2003
Japanese
Asian
HCC
125/55
PB
80/44/1
35/19/1
PCR
0.38
Kohaar 2014
Indian
Caucasian
Cervical cancer
150/200
HB
99/44/7
102/85/13
PCR-RFLP
0.40
Nieves-Ramirez 2011
Mexican
Caucasian
Cervical cancer
191/205
PB
93/82/16
114/76/15
PCR
0.64
Deshpande 2005
Hispanic
Caucasian
Cervical cancer
139/115
HB
116/22/1
84/26/5
PCR
0.12
Kesarwani 2009
Indian
Caucasian
Prostate cancer
197/256
PB
136/57/4
196/56/4
PCR
1.00
Danforth 2008
Hispanic
Caucasian
Prostate cancer
1139/1378
HB
923/203/13
1110/254/14
TaqMan
0.90
(A/B/C): A, B, and C represented the number of genotypes CC, TC, and TT, respectively; HCC, hepatocellular cancer; HWE, value for Hardy-Weinberg equilibrium for TNF-α T-857C polymorphism among controls; PCR, polymerase chain reaction; RFLP, restriction fragment length polymorphism; TaqMan, a fluorogenic exonuclease assay.
