High Interleukin-12 Levels May Prevent an Increase in the Amount of Fungi in the Gastrointestinal Tract during the First Years of Diabetes Mellitus Type 1

Table 2

Clinical characteristics of T1DM children and adolescents according to their disease duration.

	⁢Duration of diabetes			value
	Duration of diabetes ≤ 2 years	Duration of diabetes; > 2; ≤5 years	Duration of diabetes > 5 years
Age (years)	8 ± 2.7	10.4 ± 4.0	13.5 ± 2.5
HbA1c%	6.9 ± 0.6	7.8 ± 1.3	8.1 ± 1.3
hsCRP mg/dl	2.7 ± 2.3	2.0 ± 1.9	3.0 ± 2.8
IL12 pg/ml	408 ± 301	242 ± 165	201.5 ± 42.5
Yeast-like fungi 10^3–10^6 CFU/g	21%	37%	42%

Data are presented as means ± SD. with T1DM and duration of diabetes ≤ 2 years versus group > 2; ≤5 years. with T1DM and duration of diabetes ≤ 2 years versus group > 5 years. with T1DM and duration of diabetes > 2; ≤5 years versus group > 5 years.