Association of the Aspartate Aminotransferase to Alanine Aminotransferase Ratio with BNP Level and Cardiovascular Mortality in the General Population: The Yamagata Study 10-Year Follow-Up
Table 1
Clinical characteristics of subjects with high and low BNP.
Variables
All subjects
Low BNP
High BNP
value
Age (years)
<0.0001
Men/women
1562/1932
1484/1863
78/69
0.0373
Previous CVD, (%)
459 (13%)
394 (12%)
65 (44%)
<0.0001
Previous cancer, (%)
74 (2.1%)
70 (2.1%)
4 (2.7%)
0.6038
Previous liver disease, (%)
82 (2.3%)
80 (2.4%)
2 (1.4%)
0.4196
Smoking, (%)
1121 (32%)
1065 (32%)
56 (38%)
0.1106
Alcohol consumption, (%)
1454 (42%)
1390 (42%)
64 (44%)
0.6289
Hypertension, (%)
1278 (37%)
1196 (36%)
82 (56%)
<0.0001
Diabetes mellitus, (%)
241 (7%)
224 (7%)
17 (12%)
0.0225
Systolic BP, mmHg
0.0016
Diastolic BP, mmHg
0.6310
HbA1c, %
0.1783
FBS, mg/dL
0.6199
eGFR, mL/min/1.73 m2
<0.0001
Log H-FABP, ng/mL
<0.0001
AST, IU/L
0.2329
ALT, IU/L
0.0273
-GTP, IU/L
0.3517
AST/ALT ratio
<0.0001
Data are expressed as mean standard deviation or number (%). ALT, alanine transaminase; AST, aspartate transaminase; BNP, brain natriuretic peptide; BP, blood pressure; CVD, cardiovascular disease; eGFR, estimated glomerular filtration rate; FBS, fasting blood sugar; -GTP, gamma glutamyl transpeptidase; HbA1c, glycosylated hemoglobin A1c; H-FABP, heart type fatty acid binding protein.
